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Some of the possible side effects can be helped by adjusting the timing of your medication. If you have nausea, it might help to take an SSRI with food or before you go to sleep. If you have insomnia, you can try taking the medicine in the morning. If you are having sexual side effects, you can try taking it once a day and wait until after sex. Some medications, such as SSRIs, SNRIs, and TCAs, treat both conditions. A person may experience discontinuation symptoms when coming off SSRIs, including low mood and irritability.
They also cause more unpleasant side effects than SSRIs and SNRIs. If you have successfully taken an antidepressant in the past, this is always a good place to start. You are more likely to experience benefits from a medication that has worked before. But if you’ve never taken medication for depression before, healthcare providers often look at the likelihood of side effects when choosing a medication.
Ask your doctor and pharmacist about the most common possible side effects for your specific SSRI and read the patient medication guide that comes with the prescription. Everyone responds differently to SSRIs in terms of seeing improvements. People typically start noticing positive changes after about 4-6 weeks of treatment. It can take several months to feel the full effect of the medication. If you’re not feeling any improvements after about 6-8 weeks, talk to your doctor about trying another treatment or adjusting your dosage. About 9% of people taking SSRIs switch from one medication to another within the first 2 months of treatment.